fMRI Scanner Calibration Methods and Recommendations

FBIRN recommends careful scanner measurements prior to attempting to combine data across sites or MRI scanners. These can be used as Quality Assurance (QA) methods to include a site’s data in a study.

These QA scans are routinely performed and used to verify and measure the scanner stability during a typical fMRI scanning sequence. The scans are performed on a 17cm spherical phantom filled with an agar gel. The scans consist of 200 separate image volumes captured over roughly a 10-minute interval. The drift, fluctuations, signal to noise ratios, and other measures indicate the scanner’s background noise relative to its stability.

  • The instructions and analysis methods are part of the BXH/XCEDE QA tools and can be downloaded here.
  • Original versions, for archive purposes only, are available here.
  • Examples of QA measures from various scanners are here: Download will be available soon. Please check again.

Figure: Images of time series maps produced by qa_calc_fbirn.m. (A) average, (B) standard deviation, (C) noise  average, (D) SFNR.

agar_gel

BIRN is supported by NIH grants 1U24-RR025736, U24-RR021992, U24-RR021760 and by the Collaborative Tools Support Network Award 1U24-RR026057-01.