The cognitive and sensorimotor paradigms used in the Phase I Traveling Subjects (2003) and in the multisite clinical study (Phase II, 2004-2006) are available to the public.
These paradigms are available for anyone to use: Eprime Program Phase I and Eprime Programs Phase II. More paradigms used in multi-site studies are being made available.
Current recommendations on developing multi-site fMRI paradigms, and implementing them successfully, are available as part of the FBIRN Best Practices FAQ.
The Phase I and Phase II paradigms include:
- Sensorimotor tasks: Two versions of a sensorimotor task (with and without auditory stimuli, with 3Hz finger tapping or with 2Hz irregular finger tapping; one set up for 3 s TR and one for 2 s TR)
- Breath hold tasks: Two versions of a Breathhold task (one set up for a 3 s TR, using a visual circle as a cue to breathe or not; one for a 2 s TR, using red/yellow/green to cue breathing).
- Working memory tasks: Two versions of a Serial Item Recognition Paradigm (with and without an explicit motor baseline condition; one set up for 3 s TR and one for 2s TR)
- An Auditory Oddball Task
The paradigms were programmed in E-Prime and assume that each site has that software and the PST Stimulus Response Box available, though they can be modified to work with other response devices.
